NETRI MICROFLUIDIC CHIPS
PDMS based for long neural culture (up to 3 months),
all neural or glial cells types,
standardized dimensions for reproducibility.
Each chip can be coupled with MEA (Multi-Electrode Array).
DUAL 10k
deposition chamber
- Up to 10 000 neurons in a chamber
- Two independant chamber
- From 1000 to 5000 cells/mm²
- Suitable for toxicity assays and functional recordings
reference NBL1CD10
DUAL 50k
deposition chamber
- Up to 50 000 neurons in a chamber
- Two independant chambers
- From 1000 to 5000 cells/mm²
- Suitable for toxicity assays and functional recordings
reference NBL1CD50
DUAL 100k
deposition chamber
- Up to 100 000 neurons in a chamber
- Two independant chambers
- From 1000 to 5000 cells/mm²
- Suitable for toxicity assays and functional recordings
reference NBL1CD100
1M
deposition chamber
- Up to 1 000 000 neurons
in one chamber - One unique chamber
- From 1000 to 5000 cells/mm²
- Suitable for toxicity assays and functional recordings
reference NBL1CD1000
DUAL COMPARTMENT
10µm HEIGHT CONNECTION
- Two interconnected compartments
- 10-µm-high and 150-µm-large microgrooves
- From 1000 to 5000 cells/mm²
- Suitable for 3D cell seeding, scaffolding connectivity
reference NBL2XH10
DUAL COMPARTMENT
50µm HEIGHT CONNECTION
- Two interconnected compartments
- 50-µm-high and 150-µm-large microgrooves
- From 1000 to 5000 cells/mm²
- Suitable for 3D cell seeding, scaffolding connectivity
reference NBL2XH50
Triangular
chamber
- Two interconnected compartments
- From 1000 to 5000 cells/mm²
- From 200 µm to 4 mm axonal growth
- Suitable for kinetic growths and transport mechanism studies
reference NBL2XTR
100k-10k
deposition chamber
- Up to 100 000 neurons in one chamber and 10 000 in the other one
- High bidirectional double connection
- From 1000 to 5000 cells/mm²
- Suitable for transport mechanism and functional recordings
reference NBL2CD10010
Long 100K
deposition chamber
- Up to 100 000 neurons in both chambers
- High bidirectional double connection
- From 1000 to 5000 cells/mm²
- Suitable for toxicity assays, transport mechanism and functional recordings
reference NBL2CDL9
Tri-Compartment
Triangular
- Three interconnected compartments
- From 1000 to 5000 cells/mm²
- From 200 µm to 4 mm axonal growth
- Suitable for kinetic growths pre and post injury/axotomy
reference NBL3XTR
Tri-compartment
Cell Transport
- Three interconnected compartments
- From 1000 to 5000 cells/mm²
- Suitable for neuroinflammatory evaluation using microglial localization post injury
reference NBL3XADNI
TRI-COMPARTMENT
EXPLANT GROWTH
- Three interconnected compartments
- From 1000 to 5000 cells/mm²
- From 200 µm to 4 mm axonal growth
- Suitable for growth kinetics pre and post injury on full explant
reference NBLEX3XSNAIL
CST LOOP
- Five interconnected compartments
- From 1000 to 5000 cells/mm²
- Suitable for basal ganglia loop replication
- Cortex, Striatum, Thalamus, GPe and SN reproduction at 1/5 scale of rat foetal brain
reference NBM3CST
BG5 LOOP
- Five interconnected compartments
- From 1000 to 5000 cells/mm²
- Suitable for basal ganglia loop replication, with injury in SN only
- Cortex, Striatum, Thalamus, GPe and SN reproduction at 1/5 scale of rat foetal brain
reference NBM5BG5
custom designs
tailored to your needs
- From 1 to 5 compartmentalized deposit chambers
- High connectivity bidirectional connections between chambers
- Fast development process with high quality standards
- Total of 45 prototype chips
3 iterations for possible design updates
CR0 2.0
Fast and multiplexed microfluidic based screening service
- Alzheimer
- Intoxication with Amyloid beta peptide (Aβ42)
- Rodent primary neurons (hippocampal)
- Neuro-inflammatory response
- Network level response (structure and function)
- Parkinson
- Intoxication with 6-OHDA
- Rodent primary neurons (dopaminergic)
- Network level response (structure and function)