"Brain on a chip" products and services OUR SOLUTIONS Microfluidic chips Screening service

NETRI MICROFLUIDIC CHIPS

PDMS based for long neural culture (up to 3 months),
all neural or glial cells types,
standardized dimensions for reproducibility.
Each chip can be coupled with MEA (Multi-Electrode Array).
DUAL 10k
deposition chamber
  • Up to 10 000 neurons in a chamber
  • Two independant chamber
  • From 1000 to 5000 cells/mm²
  • Suitable for toxicity assays and functional recordings
reference NBL1CD10
DUAL 50k
deposition chamber
  • Up to 50 000 neurons in a chamber
  • Two independant chambers
  • From 1000 to 5000 cells/mm²
  • Suitable for toxicity assays and functional recordings
reference NBL1CD50
DUAL 100k
deposition chamber
  • Up to 100 000 neurons in a chamber
  • Two independant chambers
  • From 1000 to 5000 cells/mm²
  • Suitable for toxicity assays and functional recordings
reference NBL1CD100
1M
deposition chamber
  • Up to 1 000 000 neurons
    in one chamber
  • One unique chamber
  • From 1000 to 5000 cells/mm²
  • Suitable for toxicity assays and functional recordings
reference NBL1CD1000
DUAL COMPARTMENT
10µm HEIGHT CONNECTION
  • Two interconnected compartments
  • 10-µm-high and 150-µm-large microgrooves
  • From 1000 to 5000 cells/mm²
  • Suitable for 3D cell seeding, scaffolding connectivity
reference NBL2XH10
DUAL COMPARTMENT
50µm HEIGHT CONNECTION
  • Two interconnected compartments
  • 50-µm-high and 150-µm-large microgrooves
  • From 1000 to 5000 cells/mm²
  • Suitable for 3D cell seeding, scaffolding connectivity

reference NBL2XH50
Triangular
chamber
  • Two interconnected compartments
  • From 1000 to 5000 cells/mm²
  • From 200 µm to 4 mm axonal growth
  • Suitable for kinetic growths and transport mechanism studies

 

reference NBL2XTR
100k-10k
deposition chamber
  • Up to 100 000 neurons in one chamber and 10 000 in the other one
  • High bidirectional double connection
  • From 1000 to 5000 cells/mm²
  • Suitable for transport mechanism and functional recordings
reference NBL2CD10010
Long 100K
deposition chamber
  • Up to 100 000 neurons in both chambers
  • High bidirectional double connection
  • From 1000 to 5000 cells/mm²
  • Suitable for toxicity assays, transport mechanism and functional recordings
reference NBL2CDL9
Tri-Compartment
Triangular

 

  • Three interconnected compartments
  • From 1000 to 5000 cells/mm²
  • From 200 µm to 4 mm axonal growth
  • Suitable for kinetic growths pre and post injury/axotomy

reference NBL3XTR
Tri-compartment
Cell Transport

 

  • Three interconnected compartments
  • From 1000 to 5000 cells/mm²
  • Suitable for neuroinflammatory evaluation using microglial localization post injury
reference NBL3XADNI
TRI-COMPARTMENT
EXPLANT GROWTH

 

  • Three interconnected compartments
  • From 1000 to 5000 cells/mm²
  • From 200 µm to 4 mm axonal growth
  • Suitable for growth kinetics pre and post injury on full explant
reference NBLEX3XSNAIL
CST LOOP

 

  • Five interconnected compartments
  • From 1000 to 5000 cells/mm²
  • Suitable for basal ganglia loop replication
  • Cortex, Striatum, Thalamus, GPe and SN reproduction at 1/5 scale of rat foetal brain

reference NBM3CST
BG5 LOOP

 

  • Five interconnected compartments
  • From 1000 to 5000 cells/mm²
  • Suitable for basal ganglia loop replication, with injury in SN only
  • Cortex, Striatum, Thalamus, GPe and SN reproduction at 1/5 scale of rat foetal brain

reference NBM5BG5
Netri.fr - Prototyping
custom designs
tailored to your needs
  • From 1 to 5 compartmentalized deposit chambers
  • High connectivity bidirectional connections between chambers
  • Fast development process with high quality standards
  • Total of 45 prototype chips
    3 iterations for possible design updates

CR0 2.0
Fast and multiplexed microfluidic based screening service

  • Alzheimer
  • Intoxication with  Amyloid beta peptide (Aβ42)
  • Rodent primary neurons (hippocampal)
  • Neuro-inflammatory response
  • Network level response (structure and function)
  • Parkinson 
  • Intoxication with 6-OHDA
  • Rodent primary neurons (dopaminergic)
  • Network level response (structure and function)
Readouts : toxicity, synaptogensis, transport / growth rates and functional network activity analysis